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Tomohiko Akahoshi Selected Research

Hypersplenism (Anemia, Splenic)

11/2016Pancreatic fistula after laparoscopic splenectomy in patients with hypersplenism due to liver cirrhosis: effect of fibrin glue and polyglycolic acid felt on prophylaxis of postoperative complications.
3/2013[Total laparoscopic splenectomy for a patient with multiple surgeries including living donor liver transplantation].
10/2012Endothelin-1 derived from spleen-activated Rho-kinase pathway in rats with secondary biliary cirrhosis.
2/2012Laparoscopic splenectomy with interferon therapy in 100 hepatitis-C-virus-cirrhotic patients with hypersplenism and thrombocytopenia.
3/2010Laparoscopic splenectomy with peginterferon and ribavirin therapy for patients with hepatitis C virus cirrhosis and hypersplenism.
2/2010Laparoscopic splenectomy may be a superior supportive intervention for cirrhotic patients with hypersplenism.
1/2010Value of laparoscopic splenectomy as salvage treatment for relapsed thrombocytopenia after partial splenic arterial embolization.
1/2010Impact of antithrombin III concentrates on portal vein thrombosis after splenectomy in patients with liver cirrhosis and hypersplenism.
12/2009The feasibility and effectiveness of a hand-assisted laparoscopic splenectomy for hypersplenism in patients after living-donor liver transplantation.
1/2009Technical standardization of laparoscopic splenectomy harmonized with hand-assisted laparoscopic surgery for patients with liver cirrhosis and hypersplenism.

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Tomohiko Akahoshi Research Topics

Disease

14Liver Cirrhosis (Hepatic Cirrhosis)
11/2016 - 01/2002
11Hemorrhage
11/2020 - 01/2002
10Hypersplenism (Anemia, Splenic)
11/2016 - 01/2009
10Fibrosis (Cirrhosis)
01/2016 - 01/2002
9Esophageal and Gastric Varices (Esophageal Varices)
01/2018 - 01/2002
9Portal Hypertension
08/2015 - 05/2002
7Neoplasms (Cancer)
01/2022 - 01/2010
6Thrombocytopenia (Thrombopenia)
09/2014 - 05/2002
5Hepatocellular Carcinoma (Hepatoma)
03/2014 - 05/2002
5Varicose Veins (Varicose Vein)
12/2013 - 01/2002
5Splenomegaly
09/2013 - 09/2009
4Thrombosis (Thrombus)
02/2018 - 01/2010
3Wounds and Injuries (Trauma)
12/2019 - 01/2015
3Ulcer
12/2013 - 01/2005
3Hepatitis C
09/2013 - 06/2012
3Biliary Liver Cirrhosis (Primary Biliary Cirrhosis)
03/2013 - 08/2011
2Inflammation (Inflammations)
01/2022 - 03/2016
2COVID-19
06/2021 - 12/2020
2Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
06/2021 - 02/2021
2Respiratory Insufficiency (Respiratory Failure)
02/2021 - 12/2020
2Hypoxia (Hypoxemia)
01/2021 - 12/2007
2Infections
12/2020 - 10/2019
2Colorectal Neoplasms (Colorectal Cancer)
11/2019 - 08/2016
2Liver Diseases (Liver Disease)
02/2018 - 10/2012
2Carcinoma (Carcinomatosis)
08/2014 - 03/2013
1Nervous System Diseases (Neurological Disorders)
01/2022
1Fat Embolism
02/2021
1Reperfusion Injury
01/2021
1Non-alcoholic Fatty Liver Disease
01/2021
1Edema (Dropsy)
11/2020
1Acute Lung Injury
11/2020
1Cardiomyopathies (Cardiomyopathy)
09/2020
1Cardiotoxicity
09/2020
1Hepatitis
06/2020
1Autoimmune Hepatitis
06/2020
1Heart Rupture
12/2019
1Lacerations
12/2019
1Cardiac Tamponade
12/2019
1Residual Neoplasm
11/2019
1Alcoholic Fatty Liver
11/2019
1Carcinogenesis
11/2019
1Esophageal Neoplasms (Esophageal Cancer)
11/2019
1Chromosomal Instability (Chromosome Stability)
11/2019
1Peritonitis
10/2019

Drug/Important Bio-Agent (IBA)

6InterferonsIBA
09/2014 - 09/2009
3Pharmaceutical PreparationsIBA
11/2019 - 12/2013
3Antithrombin IIIIBA
02/2018 - 01/2010
2Reactive Oxygen Species (Oxygen Radicals)IBA
09/2020 - 11/2019
2DNA (Deoxyribonucleic Acid)IBA
11/2019 - 01/2015
2AntigensIBA
10/2016 - 01/2010
2Therapeutic UsesIBA
01/2016 - 06/2015
2Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
01/2016 - 06/2015
2EnbucrilateIBA
11/2008 - 01/2002
2salicylhydroxamic acid (SHAM)IBA
11/2008 - 01/2002
2Proteins (Proteins, Gene)FDA Link
12/2007 - 04/2007
2Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
07/2005 - 01/2005
1Fibrinogen (Factor I)FDA Link
06/2021
1AnticoagulantsIBA
06/2021
1KaolinIBA
06/2021
1Heparin Lyase (heparin lyase)IBA
06/2021
1Heparin (Liquaemin)FDA LinkGeneric
06/2021
1MetalsIBA
03/2021
1histidine-rich proteinsIBA
01/2021
1Oleic Acid (Oleate)IBA
01/2021
1GlucocorticoidsIBA
12/2020
1nafamostatIBA
12/2020
1Hydroxychloroquine (Plaquenil)FDA LinkGeneric
12/2020
1chloroquine diphosphateFDA LinkGeneric
12/2020
1Histones (Histone)IBA
11/2020
1sodium thiosulfateFDA Link
09/2020
1AntioxidantsIBA
09/2020
1Doxorubicin (Adriamycin)FDA LinkGeneric
09/2020
1Farnesyltranstransferase (Farnesyltransferase)IBA
06/2020
1Concanavalin AIBA
06/2020
1tipifarnib (R115777)IBA
06/2020
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
11/2019
1SiliconesIBA
10/2019

Therapy/Procedure

25Splenectomy
01/2018 - 01/2002
12Therapeutics
02/2021 - 05/2004
8Sclerotherapy
03/2014 - 01/2002
4Ligation
06/2013 - 11/2008
3Liver Transplantation
06/2020 - 12/2009
2Extracorporeal Membrane Oxygenation
06/2021 - 02/2021
2Transplantation
01/2021 - 10/2016
2Bariatric Surgery
11/2019 - 02/2015
2Endoscopes
11/2019 - 12/2012
2Drug Therapy (Chemotherapy)
11/2019 - 02/2010
2Pancreaticoduodenectomy
08/2014 - 03/2013
2Length of Stay
04/2012 - 01/2002
2Injections
01/2002 - 01/2002
1Precision Medicine
01/2022
1Surgical Instruments (Clip)
03/2021
1Tattooing
03/2021
1Perioperative Period
02/2021
1Artificial Respiration (Mechanical Ventilation)
12/2020
1Sternotomy
12/2019
1Thoracotomy
12/2019
1Sutures (Suture)
12/2019
1Operative Surgical Procedures
11/2019
1Negative-Pressure Wound Therapy
10/2019